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CB / CB-UL, CBF / CBF-UL (E7) 07/2021 Page 18/197
1.10 Intended use
Following the instructions in this operating manual and conducting regular maintenance work
(chap. 22.5) are part of the intended use.
Any use of the chambers that does not comply with the requirements specified in this Operating
Manual shall be considered improper use.
Other applications than those described in this chapter are not approved.
Use
CB / CB-UL and CBF / CBF-UL incubators are suitable for the cultivation of mammal cells under typical
conditions of approx. 37 °C / 98.6°F. The chamber permits setting defined pH conditions by common
NaHCO
3
buffer systems of commercial cell media by keeping an exact CO
2
atmosphere inside. The
chambers guarantee high humidity inside to avoid osmolarity increasing caused by the evaporation of the
cell media.
With the chamber with O
2
control, a variable oxygen atmosphere can additionally influence the growth of
the cells.
The chambers are suitable for exact conditioning of harmless materials.
Requirements for the chamber load
Any solvent must not be explosive and flammable. Components of the charging material must NOT form
an explosive mixture with air. The operating temperature must lie below the flash point or below the
sublimation point of the charging material. Any component of the charging material must NOT be able to
release toxic gases.
The charging material shall not contain any corrosive ingredients that may damage the machine
components made of stainless steel, aluminum, and copper. Such ingredients include in particular acids
and halides. Any corrosive damage caused by such ingredients is excluded from liability by BINDER GmbH.
The chamber does not dispose of any measures of explosion protection.
DANGER
Explosion or implosion hazard and danger of poisoning through the introduction of
unsuitable loading material.
Poisoning. Serious injury or death from burns and / or explosion pressure.
∅ Do NOT introduce any substance combustible or explosive at working temperature into
the chamber, in particular no energy sources such as batteries or lithium-ion batteries.
∅ NO explosive dust or air-solvent mixture in the inner chamber.
∅ Do NOT introduce any substance which could lead to release of toxic gases.
Contamination of the chamber by toxic, infectious or radioactive substances must be prevented
WARNING
Danger of intoxication and infection through contamination of the chamber with
toxic, infectious or radioactive substances.
Damages to health.
Protect the interior of the chamber from contamination by toxic, infectious or radioactive
substances.
Take suitable protective measures when introducing and removing toxic, infectious or
radioactive material
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